Senior Director Translational Sciences in Basking Ridge, New Jersey at DSI

Date Posted: 1/6/2020

Job Snapshot

Job Description

Join a Legacy of Innovation 110 Years and Counting!

With over 100 years of scientific expertise and a presence in more than 20 countries, Daiichi Sankyo and its 15,000 employees around the world draw upon a rich legacy of innovation and a robust pipeline of promising new medicines to help people. In addition to a strong portfolio of medicines for hypertension and thrombotic disorders, under the Group’s 2025 Vision to become a “Global Pharma Innovator with a Competitive Advantage in Oncology,” Daiichi Sankyo research and development is primarily focused on bringing forth novel therapies in oncology, including immuno-oncology, with additional focus on new horizon areas, such as pain management, neurodegenerative diseases, heart and kidney diseases, and other rare diseases.

Job Summary:

The position will define and oversee the translational medicine strategy for a drug program across multiple indications. The successful candidate will set goals and enumerate key scientific questions that will drive clinical development decision-making. In doing so, he or she will align closely with the Global Project Team and Global Team Leader as well as counterparts overseeing research and translational activities in the laboratories in Japan. In addition, he or she will interact with counterparts in the Companion Diagnostics group to support the program. Other responsibilities will include but not be limited to identifying and interacting with key external experts and monitoring progress toward goals of external research programs. Lastly, he or she will be responsible for constructing translational plan documents, biomarker statistical analysis plans, and aid in the construction of clinical development plans, clinical protocols, and in the submission of certain regulatory documents, as well as supporting commercial in developing a strategy including patient selection strategy.

Responsibilities:
  • Develop and maintain a translational plan for the program across all indications. Define key scientific questions and steps taken to answer them.
  • With the Companion Diagnostics group, develop a companion diagnostic plan for the program across all indications as needed. Choose developmental paths for the diagnostics including partnerships and external collaborations.
  • Identify and interact with key external experts, defining scientific questions to be answered. Monitor progress toward goals of external research programs.
  • Construct translational plan documents, biomarker statistical analysis plans, and aid in the construction of clinical development plans, clinical protocols, and in the submission of certain regulatory documents. Support commercial in developing a strategy including patient selection strategy.
  • Construct and co-lead Advisory Panels at certain scientific conferences. Lead the Translational Subteam within the Global Project Team for the drug program. Present as needed at internal and external meetings.
Qualifications
Successful candidates will be able to meet the qualifications below with or without a reasonable accommodation.

Education/Experience:
  • PharmD, PhD, MD or equivalent; Postgraduate training in TA (oncology) or related specialty.
  • Minimum of 5+ (MD), 7+ (PharmD, PhD) years of experience in translational oncology drug development at a biopharmaceutical company
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.